Descrizione

Prostate cancer imaging has evolved rapidly dur¬ing the last years, moving toward a more person¬alized approach. The comprehensive evaluation of tumor biology alongside the evaluation of different patterns of expression by cancer clones has become an attractive field of investigation for molecular imaging. Next-generation imaging represents a ground-breaking approach, deliver¬ing to patients more accurate diagnostic proce¬dures and leading clinicians to identify specific targets for radioligand therapy. The theragnos¬tic approach-therapy and diagnosis using the same probe-represents, probably, one of the most important innovations in the management of prostate cancer. Hence, the rapid introduction into clinical practice of small molecules bind¬ing prostate-specific membrane antigen (PSMA) represents a brilliant example of how transla¬tional imaging should work. Prostate cancer, as one of the most frequent tumors and causes of death, still represents a hard enemy to fight, but next-generation imaging and radioligand therapy are innovative weapons that might contribute to improve outcomes and quality of life in men affected by the disease.